10 New Anime Releasing In April 2025 You Don’t Want To Miss

April 2025 is packed with new anime premieres, and there’s a lot to sort through. If you’ve been feeling a bit lost with all the trailers and updates, here’s a quick breakdown of 10 new shows coming next month that are getting a lot of attention.

This list includes everything from sci-fi thrillers to fantasy action and slice-of-life stories. Whether you’re into serious plots or something more fun, you’ll probably find something worth checking out here.

Note: Anime Sequels are not included in this list. 

1. Lazarus

This original series starts with a peaceful future where a drug called Hapuna cures all illness and pain. But three years later, the drug’s creator announces that it will kill anyone who took it. With just 30 days left before the drug becomes fatal, a group called Lazarus is formed to find him and prevent disaster.

The animation is handled by MAPPA, with direction by Watanabe (Cowboy Bebop) and action design by Stahelski. The mix of talent from both anime and live-action brings a lot of expectations. Worth keeping an eye on if you enjoy intense storytelling and strong visuals.

2. My Hero Academia: Vigilantes

This side story is set five years before the main My Hero Academia series. It follows Koichi Haimawari, a college student with a low-level quirk who teams up with others working outside the official hero system. They include Knuckle Duster, a guy without a quirk who still finds a way to fight back.

With staff returning from the main series, fans can expect a familiar art style and tone. It focuses more on small-scale problems and street-level action, offering a different perspective on the larger MHA setting.

3. Can A Boy-Girl Friendship Survive?

This one is a more grounded high school story. Yatsu and Himari have been best friends since middle school. But when Yatsu reconnects with his old crush, Himari starts to question how she really feels.

The show comes from J.C. Staff, known for solid work on romance series like Toradora. It looks like a character-driven story with relatable themes, humor, and emotional moments. A strong pick if you’re into slower, more personal stories.

4. The Beginning After The End

This one adapts the web novel by TurtleMe. It starts with a powerful king, Grey, who dies and is reborn as a baby named Arthur in a fantasy world. Unlike most isekai leads, Arthur keeps all his memories and skills, giving him a major head start in learning magic and combat.

There are 24 episodes planned, and the anime has a cast that includes Makoto Furukawa (Saitama from One Punch Man) and Natsumi Fujiwara (Damian in Spy x Family). It should appeal to fans of long-form fantasy and reincarnation stories.

5. From Old Country Bumpkin to Master Swordsman

The title is long, but the idea is pretty simple. Barl Gardet is a sword teacher from a small village. Years later, his former students who’ve all become powerful warriors and mages track him down and invite him to help train a top knight squad. He goes from quiet village life to working with elite fighters who still see him as a hero.

With a cast led by Hiroaki Hirata (Sanji from One Piece), the show blends comedy and action with moments of heart. Probably a good pick for viewers who enjoy light fantasy with character humor.

6. Sword of the Demon Hunter – Kijin Gintou

This one technically starts on the last day of March, but it’s definitely part of the spring season. Sword of the Demon Hunter begins with a 1-hour special episode, which means they’re really trying to make a strong first impression.

The anime takes place in Edo-period Japan and follows a guy named Genta, who watches over a shrine in his village. One day he runs into a demon in the woods who tells him a demon god is going to rise from the village—but not for hundreds of years.

So the story becomes about Genta trying to stop that from ever happening by traveling through time and dealing with all kinds of people and creatures. It was delayed from last year, so fans have been waiting for this one.

7. The Brilliant Healer’s New Life in the Shadows

This anime is about Zenos, a really skilled healer who gets kicked out of his adventuring party—even though he’s super talented. Instead of giving up, he starts a secret clinic in the darker parts of the city, helping people who usually get ignored by society.

Along the way, he saves an elf girl named Lily from slavery, and she becomes his assistant. The story is all about people getting second chances, and how someone can still make a difference even when the world pushes them aside.

8. Kowloon Generic Romance

Set in the legendary and chaotic Kowloon Walled City, this anime has a very cool vibe. The main character is Reiko Kujira, a real estate agent who works for a company called Wongai Properties. She’s got a crush on her coworker Hajime Kudo, who’s obsessed with the city’s history.

But then Reiko finds a photo that shows Kudo’s ex-fiancée looked exactly like her. That kicks off a mystery that mixes romance and strange secrets hidden in the city. The whole setting has this surreal, dreamlike feel, and it looks like the anime really leans into that atmosphere.

9. Witch Watch

Witch Watch is a fun-looking magical slice-of-life anime that follows Nico Wakatsuki, a teenage witch who just finished her training. She moves in with her childhood friend Morio Otoki, who is actually an ogre. Because of a deal between their families, Morio is now her familiar and bodyguard.

They end up living together and going to school, but of course, it’s not your regular high school—there’s magic, chaos, and lots of awkward moments. Nico’s spells are super powerful but very unpredictable, which causes all kinds of problems.

10. The Shunji Family Children

The most emotional pick on the list is The Shunji Family Children, which tells the story of a large family that gets shocking news: none of the siblings are actually related by blood.

The focus is on Ara Shunji, who lives with five sisters and one younger brother. When their dad drops the truth on them, it completely changes how they see themselves and each other. The story explores what it means to be a family when biology isn’t what connects you. Expect a lot of heartfelt drama and personal growth in this one.

The anime comes from Doga Kobo, a studio known for strong character-driven shows like Shikimori’s Not Just a Cutie.